Antibodies in Charles"" immune system had developed to fight the 112 virus, so that the effects of the gene therapy diminished, and he disease started to "return with a vengeance...Oh, Johnny, I""m beggin"" ya! Oh, please take me with ya! Don""t leave me here, Johnny, please..." As Johnny fled out the door to chase after Cullen, Billy shot him in the shoulder.When Johnny caught up to Cullen, he revealed: "That woman told you wrong." He explained her rationale for lying - she feared that if Cullen was caught, he would squeal.The authorities arrived and questioned the woman, asking if the fugitives had taken anything.Uncooperative, she replied knowingly (implying that she had sex with Johnny): "Nothin"" you could put ""em in jail for." De Winter reveals an air of mystery and independence by traveling alone and by his sudden departure prefaced with a motto: "I""m afraid I cling to the old motto: ""He travels fastest who travels alone.Bedford Falls comes slowly into focus.It is the year 1919 and young native George Bailey (Bobbie Anderson) is 12 years old - born, raised, and educated in Bedford Falls.